e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Canadian journal of chemistry

Chemistry of spectinomycin: its total synthesis, stereocontrolled rearrangement, and analogs

S Hanessian, R Roy

Index: Canadian Journal of Chemistry, , vol. 63, # 1 p. 163 - 172

Full Text: HTML

Citation Number: 48

Abstract

... product were successfully correlated with a known substance, then the task of assigning an absolute stereo- chemistry would be ... In the hope of achieving structural and stereochemical convergence, we proceeded with a chemical modification program on two fronts. ... J,,,., 8 Hz ...

N,N-bis(benzyloxycarbonyl)-spectinomycin Structure

N,N-bis(benzylo...

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Spectinomycin Structure

N/A Structure

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Spectinomycin Structure

dibenzyl ((1R,2S,3S,4R,5r,6S)-5-(((3aR,4S,6R,7aR)-2-methoxy-2,6-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyran-4-yl)oxy)-2,4,6-tris(((2,2,2-trichloroethoxy)carbonyl)oxy)cyclohexane-1,3-diyl)bis(methylcarbamate) Structure

dibenzyl ((1R,2...

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Spectinomycin Structure

N/A Structure

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Spectinomycin Structure

(2S,4R,6R)-2-(((1r,2R,3S,4S,5R,6S)-3,5-bis(((benzyloxy)carbonyl)(methyl)amino)-2,4,6-tris(((2,2,2-trichloroethoxy)carbonyl)oxy)cyclohexyl)oxy)-6-methyl-3-oxotetrahydro-2H-pyran-4-yl acetate Structure

(2S,4R,6R)-2-((...

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Spectinomycin Structure

N,N'-Bis-(carbobenzyloxy)dihydrospectinomycin Structure

N,N'-Bis-(carbo...

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Spectinomycin Structure

Spectinomycin dihydrochloride Structure

Spectinomycin d...

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Spectinomycin Structure

N/A Structure

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Spectinomycin dihydrochloride Structure

Spectinomycin d...

dibenzyl ((1R,2S,3S,4R,5r,6S)-5-(((3aR,4S,6R,7aR)-2-methoxy-2,6-dimethyltetrahydro-4H-[1,3]dioxolo[4,5-c]pyran-4-yl)oxy)-2,4,6-tris(((2,2,2-trichloroethoxy)carbonyl)oxy)cyclohexane-1,3-diyl)bis(methylcarbamate) Structure

dibenzyl ((1R,2...

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Spectinomycin dihydrochloride Structure

Spectinomycin d...

N/A Structure

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Spectinomycin dihydrochloride Structure

Spectinomycin d...

(2S,4R,6R)-2-(((1r,2R,3S,4S,5R,6S)-3,5-bis(((benzyloxy)carbonyl)(methyl)amino)-2,4,6-tris(((2,2,2-trichloroethoxy)carbonyl)oxy)cyclohexyl)oxy)-6-methyl-3-oxotetrahydro-2H-pyran-4-yl acetate Structure

(2S,4R,6R)-2-((...

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Spectinomycin dihydrochloride Structure

Spectinomycin d...

N,N'-Bis-(carbobenzyloxy)dihydrospectinomycin Structure

N,N'-Bis-(carbo...

~%

Spectinomycin dihydrochloride Structure

Spectinomycin d...