Chloroethylating and methylating dual function antineoplastic agents display superior cytotoxicity against repair proficient tumor cells

R Zhu, RP Baumann, E Patridge, PG Penketh…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 6 p. 1853 - 1859

Full Text: HTML

Citation Number: 3

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... Developmental Therapeutics Program, Yale Comprehensive Cancer Center, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520-8066, United States. ...

 Related Synthetic Route
1,2-BIS(METHYLSULFONYL)-1-(2-CHLOROETHYL)HYDRAZINE Structure

127792-84-1

1,2-BIS(METHYLS...

~%

2-Chloroethanol Structure

107-07-3

2-Chloroethanol

1-[2-chloroethyl(methylsulfonyl)amino]-3-methyl-1-methylsulfonylurea Structure

173424-77-6

1-[2-chloroethy...

~%

2-Chloroethanol Structure

107-07-3

2-Chloroethanol

2-(2-chloroethyl)-N-methyl-1,2-bis(methylsulfonyl)-N-nitrosohydrazinecarboxamide Structure

1426658-55-0

2-(2-chloroethy...

~%

Methanol Structure

67-56-1

Methanol

2-Chloroethanol Structure

107-07-3

2-Chloroethanol

N-(2-chloroethyl)-2-methyl-1,2-bis(methylsulfonyl)-N-nitrosohydrazinecarboxamide Structure

1426658-59-4

N-(2-chloroethy...

~%

Methanol Structure

67-56-1

Methanol

2-Chloroethanol Structure

107-07-3

2-Chloroethanol

2-(2-chloroethyl)-N-methyl-1,2-bis(methylsulfonyl)-N-nitrosohydrazinecarboxamide Structure

1426658-55-0

2-(2-chloroethy...

2,4-Dinitrophenylhydrazine Structure

119-26-6

2,4-Dinitrophen...

~%

Formaldehyde,2-(2,4-dinitrophenyl)hydrazone Structure

1081-15-8

Formaldehyde,2-...

N-(2-chloroethyl)-2-methyl-1,2-bis(methylsulfonyl)-N-nitrosohydrazinecarboxamide Structure

1426658-59-4

N-(2-chloroethy...

2,4-Dinitrophenylhydrazine Structure

119-26-6

2,4-Dinitrophen...

~%

Acetaldehyde,2-chloro-, 2-(2,4-dinitrophenyl)hydrazone Structure

5135-80-8

Acetaldehyde,2-...

Formaldehyde,2-(2,4-dinitrophenyl)hydrazone Structure

1081-15-8

Formaldehyde,2-...

2-(2-chloroethyl)-N-methyl-1,2-bis(methylsulfonyl)-N-nitrosohydrazinecarboxamide Structure

1426658-55-0

2-(2-chloroethy...

2,4-Dinitrophenylhydrazine Structure

119-26-6

2,4-Dinitrophen...

~%

Acetaldehyde,2-chloro-, 2-(2,4-dinitrophenyl)hydrazone Structure

5135-80-8

Acetaldehyde,2-...

Formaldehyde,2-(2,4-dinitrophenyl)hydrazone Structure

1081-15-8

Formaldehyde,2-...


Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved