Tetrahedron letters

Methyl 3-phenylsulphonyl orthopropionate: an efficient reagent for the synthesis of γ-lactones and butenolides

JC Carretero, S De Lombaert, L Ghosez

Index: Carretero, Juan Carlos; Lombaert, Stephane De; Ghosez, Leon Tetrahedron Letters, 1987 , vol. 28, # 19 p. 2135 - 2138

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Citation Number: 32

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Treatment of methyl 3-phenylsulphonyl orthopropionate with n-BuLi gives the corresponding carbanion which reacts with aldehydes or ketones to yield β-phenylsulphonyl γ-lactones. Base-catalysed elimination of sulphinic acid yields α,β or β,γ-butenolides.