A convenient synthesis of 1-alkyl-1-phenylhydrazines from N-aminophthalimide

…, T Sakamoto, E Miyazawa, Y Kikugawa

Index: Nara, Shigeru; Sakamoto, Takeshi; Miyazawa, Etsuko; Kikugawa, Yasuo Synthetic Communications, 2003 , vol. 33, # 1 p. 87 - 98

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Citation Number: 20

Abstract

Abstract N-Alkylaminophthalimides were synthesized by condensation of N- aminophthalimide with aldehydes, and subsequent reduction of the intermediate with pyridine-borane in acetic acid. N-Phenylation and removal of the phthalimide group gave 1- alkyl-1-phenylhydrazines in high yield.