Journal of the Chinese Chemical Society

Syntheses of Hitherto Unknown Thiazole, Ylidene and Pyridinethione Derivatives Having a Piperidin??1??yl Moiety and Their Use as Antimicrobial Agents

MSA El??Gaby

Index: El-Gaby, Mohamed Sayed A. Journal of the Chinese Chemical Society, 2004 , vol. 51, # 1 p. 125 - 134

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Citation Number: 31

Abstract

Abstract The novel hydrazone derivatives 2a-c were prepared by treatment of aldehydes 1a, b with some hydrazines. Thiocarbamoyl functional group in compound 2a was subjected to cyclization reactions with some α-halocarbonyl reagents and furnished the novel thiazoles 4- 6, 8 and 9. Enaminonitrile 10 and pyridinone 13 derivatives were synthesized by interaction of active methylene compound 2b with N, N-dimethylformamide-dimethylacetal and ...