Abstract The title compound was prepared by the isocyanate procedure and the tri- methylsilyl method. The measurement of 1H NMR spectrum of 6-methyl-5-azacytidine (1) revealed a preference of γt (46%) rotamer around C (5′)-C (4′) bond, a predominance of N conformation of the ribose ring (Keq 0.33) and a preference of syn conformation around the CN glycosyl bond. An analogous measurement of 5-azacytidine has shown a ...
[Howell, Henry G.; Brodfuehrer, Paul R.; Brundidge, Steven P.; Benigni, Daniel A.; Sapino, Chester Journal of Organic Chemistry, 1988 , vol. 53, p. 85 - 88]
