Substituted carboxylic acid hydrazides 1a–d reacted with ethenetetracarbonitril 2 in dimethyl formamide with the formation of diacylhydrazines 4a–d and 5-amino-1-substiuted pyrazole- 3, 3, 4-tricarbonitriles 5a–d. On the other hand, 1a–d reacted with diethyl (E)-2, 3- dicyanobutenedioate 3 to give oxadiazole derivatives 10a–d and pyrazolone derivatives 11a–d, respectively. The prepared compounds 4a–d, 5a–d and 11a–d were evaluated ...