e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Chemistry of novel compounds with a multifunctional carbon structure. 5. Molecular design of versatile building blocks for aliphatic monofluoro molecules by …
Three kinds of doubly functionalized monofluoromethylene fragments, 1-fluoro-1-nitro-1- (phenylsulfony1) alkanes (lo), 2-fluoro-2-(phenylsulfonyl) alkanoic esters (1 l), and 2-fluoro-2- nitroalkanoic esters (12), potentially versatile building blocks for the general synthesis of various aliphatic monofluoro molecules, were prepared from the corresponding difunctional compounds 1-3 by monoalkylations (R) and selective fluorinations. The interconversion or ...