Some 1, 5-dihydro-5-deazaflavin (1, 5-dihydropyrimido [4, 5-b] quinoline-2, 4 (3H, 10H)- dione) derivatives possessing chiral substituents at the N-3 position were synthesized. Asymmetric reduction of ethyl benzoylformate in the presence of magnesium perchlorate was carried out with these chiral 1, 5-dihydro-5-deazaflavin derivatives to give ethyl mandelate in moderate optical and chemical yield. The influence of metal additives other ...
