Tetrahedron

An efficient stereocontrolled synthesis of 12 (R)-HETE and 12 (S)-HETE

D Chemin, S Gueugnot, G Linstrumelle

Index: Chemin, Denis; Gueugnot, Sylvie; Linstrumelle, Gerard Tetrahedron, 1992 ,  vol. 48,  # 21  p. 4369 - 4378

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Citation Number: 15

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... An efficient synthesis of 12(R) and 12(S) HETEs was realized by assembly of the easily obtainable synthons: optically pure iodo-alcohols 3(R) and 3(S) with the ester 4, followed by reduction with activated zinc. ... The enantiomeric excess was determined according to a new ( ...