e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
High-affinity leukotriene receptor antagonists. Synthesis and pharmacological characterization of 2-hydroxy-3-[(2-carboxyethyl) thio]-3-[2-(8-phenyloctyl) phenyl] …
…, CD Perchonock, KF Erhard, JS Frazee…
Index: Gleason, John G.; Hall, Ralph F.; Perchonock, Carl D.; Erhard, Karl F.; Frazee, James S.; et al. Journal of Medicinal Chemistry, 1987 , vol. 30, # 6 p. 959 - 961
2 discovery of a series of [(phenyloctyl) phenyl] propionic acids as novel, potent, specific, high-affinity peptidoleukotriene receptor antagonists. The syntheses and pharmacological profile of two members of this class, 3-[(2-carboxyethyl) thio]-3-[2-(8-phenylocty1) phenyllpropionic acid (1) and B (S)-hydroxy-3 (R)-[(2-carboxy-ethyl) thio]-3-[2-(8- phenyloctyl) phenyl] propionic acid (2a,
![methyl-α-hydroxy-β-[(2-(methoxycarbonyl)ethyl)thio]-2-(8-phenyloctyl)benzenepropanoate Structure](https://image.chemsrc.com/caspic/340/120427-74-9.png)
![2(S)-hydroxy-3(R)-(2-carboxyethylthio)-3-[2(8-phenyloctyl)phenyl]-propanoic acid Structure](https://image.chemsrc.com/caspic/424/107023-40-5.png)
![((+/-)-trans)-Methyl 3-[2-(8-phenyloctyl)phenyl]oxiranecarboxylate Structure](https://image.chemsrc.com/caspic/083/108082-09-3.png)