Tetrahedron Letters

'ClickCarb': modular sugar based ligands via click chemistry

N Khiar, R Navas, I Fernández

Index: Khiar, Noureddine; Navas, Raquel; Fernandez, Inmaculada Tetrahedron Letters, 2012 , vol. 53, # 4 p. 395 - 398

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Citation Number: 16

Abstract

Reported is a modular approach for the synthesis of a number of structurally diverse ligands derived from carbohydrates. The use of the highly functional hydroxy amino azide 1 derived from glucosamine allows the synthesis of a number of useful ligands for organic and organometallic catalyses. The key step of the approach is the Huisgen cycloaddition of the anomeric sugar azide and diverse alkynes.