Fluorinated indazoles as novel selective inhibitors of nitric oxide synthase (NOS): Synthesis and biological evaluation

RM Claramunt, C López, C Pérez-Medina…

Index: Bioorganic and Medicinal Chemistry, , vol. 17, # 17 p. 6180 - 6187

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Citation Number: 35

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry. ... 3. Conclusions. A major challenge of modern medicine is to design compounds that modulate specific enzymes while leaving related isozymes unaffected. ...