Tetrahedron

Efficient use of a surfactant for copper-catalyzed coupling reaction of arylboronic acids with imidazoles in water

K Inamoto, K Nozawa, J Kadokawa, Y Kondo

Index: Inamoto, Kiyofumi; Nozawa, Kanako; Kadokawa, Jun; Kondo, Yoshinori Tetrahedron, 2012 , vol. 68, # 38 p. 7794 - 7798

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Citation Number: 13

Abstract

Copper-catalyzed oxidative coupling of arylboronic acids with imidazoles in water was realized by using an amphiphilic surfactant. By choosing an appropriate surfactant, reactions of a variety of arylboronic acids proceeded smoothly under mild and base-free conditions, providing an efficient, practical, and greener method for the synthesis of N-arylimidazoles.