5-Alkylresorcinols from Hakea trifurcata, that cleave DNA.

…, VS Murty, KS Reddy, JR Barr, SM Hecht

Index: Lytollis, William; Scannell, Ralph T.; An, Haoyun; Murty; Reddy, K. Sambi; Barr, John R.; Hecht, Sidney M. Journal of the American Chemical Society, 1995 , vol. 117, # 51 p. 12683 - 12690

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Citation Number: 68

Abstract

Abstract: A dichloromethane extract of Hakea trifurcata that mediated relaxation of 4x174 replicative form DNA at micromolar concentrations in the presence of Cu2+ was resolved into six active components by bioassay-guided fractionation. Five of the active principles were characterized structurally and shown to be 5-alkylresorcinol derivatives.

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3,5-Dimethoxybenzaldehyde Structure

7311-34-4

3,5-Dimethoxybe...

~%

1-[14-(3,5-dimethoxyphenyl)tetradecyl]-3,5-dimethoxybenzene Structure

21390-07-8

1-[14-(3,5-dime...

1,3-dimethoxy-5-(5-hydroxypentyl)benzene Structure

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1-[14-(3,5-dimethoxyphenyl)tetradecyl]-3,5-dimethoxybenzene Structure

21390-07-8

1-[14-(3,5-dime...

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886-52-2

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1-[14-(3,5-dimethoxyphenyl)tetradecyl]-3,5-dimethoxybenzene Structure

21390-07-8

1-[14-(3,5-dime...

1-(1-hydroxypentyl)-3,5-dimethoxybenzene Structure

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1-(1-hydroxypen...

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1-[14-(3,5-dimethoxyphenyl)tetradecyl]-3,5-dimethoxybenzene Structure

21390-07-8

1-[14-(3,5-dime...

(E)-1-(3,5-dimethoxyphenyl)pent-1-ene Structure

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(E)-1-(3,5-dime...

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1-[14-(3,5-dimethoxyphenyl)tetradecyl]-3,5-dimethoxybenzene Structure

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1,3-dimethoxy-5-(6'-heptynyl)benzene Structure

50873-97-7

1,3-dimethoxy-5...

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1-[14-(3,5-dimethoxyphenyl)tetradecyl]-3,5-dimethoxybenzene Structure

21390-07-8

1-[14-(3,5-dime...

N/A Structure

171569-33-8

N/A

~%

1-[14-(3,5-dimethoxyphenyl)tetradecyl]-3,5-dimethoxybenzene Structure

21390-07-8

1-[14-(3,5-dime...

5-(7'-bromoheptyl)-1,3-dimethoxybenzene Structure

55009-70-6

5-(7'-bromohept...

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1-[16-(3,5-dimethoxyphenyl)hexadec-8-ynyl]-3,5-dimethoxybenzene Structure

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5-(7'-bromoheptyl)-1,3-dimethoxybenzene Structure

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5-(7'-bromohept...

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1-[16-(3,5-dimethoxyphenyl)hexadec-8-ynyl]-3,5-dimethoxybenzene Structure

61621-79-2

1-[16-(3,5-dime...

3,5-Dimethoxybenzaldehyde Structure

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3,5-Dimethoxybe...

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grevillol Structure

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grevillol

5-(1-hydroxytridecyl)-1,3-dimethoxybenzene Structure

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5-(1-hydroxytri...

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grevillol Structure

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1-Bromododecane Structure

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1-Bromododecane

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grevillol Structure

5259-01-8

grevillol

Benzene, 1,3-dimethoxy-5-(1-tridecenyl)-, (E)- Structure

171569-31-6

Benzene, 1,3-di...

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grevillol Structure

5259-01-8

grevillol

Benzene, 1,3-dimethoxy-5-(1-tridecenyl)-, (E)- Structure

171569-31-6

Benzene, 1,3-di...

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1,3-dimethoxy-5-tridecylbenzene Structure

5259-04-1

1,3-dimethoxy-5...

1-Bromododecane Structure

143-15-7

1-Bromododecane

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1,3-dimethoxy-5-tridecylbenzene Structure

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1,3-dimethoxy-5...


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