Tetrahedron

Synthesis and conformational analysis of 2-methylthioderivatives of 1-(2'-furyl) ethanol and their O-methyl derivatives

…, I Fernández, M Trujillo, F Zorrilla, E Marhuenda

Index: Alcudia, F.; Fernandez, I.; Trujillo, M.; Zorrilla, F.; Marhuenda, E. Tetrahedron, 1989 , vol. 45, # 5 p. 1491 - 1500

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Citation Number: 5

Abstract

The synthesis and conformational analysis of some β-thioderivatives of 1-(2'-furyl) ethanol and their O-methyl derivatives, Ar-CHX-CH2-Y (X: OH and OMe; Y: SMe, SOMe and SO2Me), are reported. The conformational equilibria have been established from 1H-nmr data and high dilution ir studies. Immunosuppressive properties of (methylsulphinyl) methyl 2-furyl ketone and 2-(methylsulphinyl)-1-(2'-furyl) ethanol,(RR/SS) and (RS/SR), have ...