Organic letters

Overcoming Regioselectivity Issues Inherent in Bis-Tröger's Base Preparation

M Havlík, V Král, B Dolenský

Index: Kauffmann; Beisswenger Chemische Berichte, 1904 , vol. 37, p. 2610

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Citation Number: 17

Abstract

... Volume: Page: ... Treatment of diacid 2 with SOCl 2 or (COCl) 2 followed by p-anisidine always afforded monoamide 4 with no traces of diamide 3 or imide 5a (Scheme 1). This can be explained by the formation of anhydride 6. 12 Fortunately, the treatment of ...