Tetrahedron letters

A highly efficient method for the synthesis of guanidinium derivatives

JC Manimala, EV Anslyn

Index: Manimala, Joseph C; Anslyn, Eric V Tetrahedron Letters, 2002 , vol. 43, # 4 p. 565 - 567

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Citation Number: 34

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A high yielding synthesis of guanidiniums with the use of the ethyl carbamate protecting group is presented. This strategy eliminates many steric hindrance and electronic problems. The deprotection of the products by Me 3 SiBr is also demonstrated. ... The coupling of an amide to the ethyl ...