Tetrahedron

Synthesis of the calothrixins, pentacyclic indolo [3, 2-j] phenanthridine alkaloids, using a biomimetic approach

CSP McErlean, J Sperry, AJ Blake, CJ Moody

Index: McErlean, Christopher S.P.; Sperry, Jonathan; Blake, Alexander J.; Moody, Christopher J. Tetrahedron, 2007 , vol. 63, # 45 p. 10963 - 10970

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Citation Number: 31

Abstract

Oxidation of the indolo [2, 3-a] carbazole 16, readily obtained in six steps from indigo, followed by deprotection results in formation of the indolo [3, 2-j] phenanthridine quinone alkaloid calothrixin B 2, demonstrating the viability of the proposed biosynthetic route to this unique ring system.