Effect of Hofmeister series anions on the thermotropic phase behavior of bioactive O-acylcholines

PK Tarafdar, ST Reddy, MJ Swamy

Index: Tarafdar, Pradip K.; Reddy, S. Thirupathi; Swamy, Musti J. Journal of Physical Chemistry B, 2013 , vol. 117, # 34 p. 9900 - 9909

Full Text: HTML

Citation Number: 9

Abstract

O-Acylcholines (OACs), which are true cationic lipids due to the quaternary ammonium functionality in the headgroup, exhibit interesting biological activities and medicinal properties. In the present study, a homologous series of OACs with even chain lengths (n= 12–20) have been synthesized, and their thermotropic and chaotropic phase transitions have been characterized. The role of various anions (Cl–, Br–, I–, NO3–, SO42–, ClO3–, ...