American Cyanamid Company, Medical Research Division, Lederle Laboratories, Pearl River, New York 10965. Received August 24, 1988 [l, l-Cyclobutanedicarboxylato (2-)-O, O'l (1, 3-dioxane-5, 5-dimethanamine-N, N~ platinum (II), 3a, a third generation, very water- soluble platinum complex, has been synthesized along with several of its analogues. All members of the new family contain a 1, 3-dioxane or 1, 3-dioxolane-l, 3-diamine as their ...
