Trichloroisocyanuric Acid Oxidation of 2-Chloro Aldehyde Acetals to 2-Chloro Acid Esters.

M Boni, F Ghelfi, UM Pagnoni, A Pinetti

Index: Boni, Monica; Ghelfi, Franco; Pagnoni, Ugo Maria; Pinetti, Adriano Bulletin of the Chemical Society of Japan, 1994 , vol. 67, # 1 p. 156 - 159

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Citation Number: 9

Abstract

2-Chloro acid methyl esters were prepared in good yields treating 2-chloro aldehyde dimethyl acetals with trichloroisocyanuric acid in DMF. Aldehyde dimethyl acetals with the 2- halogen on a tertiary carbon atom were poorly reactive and could be oxidized effeciently only after their transformation into 1, 3-dioxolanes.