Journal of the American Chemical Society

The Action of Hydrochloric and Nitric Acids on Some Derivatives of Phenothiazine1

AC Schmalz, A Burger

Index: Schmalz; Burger Journal of the American Chemical Society, 1954 , vol. 76, p. 5455,5457

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Citation Number: 36

Abstract

The formation of 3-chloro-10-methylphenothiazine(IV) by reductive chlorination of 10- methylphenothiazine-S-oxide(I) has been confirmed by synthesis of IV. Under similar conditions l0-(3-diethylaminopropyl)-phenothiazine-5-oxide gave 3 (?)-chloro-lO-(3- diethylamixiopropyl)-phenothiazine while l0-(3-diethylaminopropyl)-phenothiazine-~, 5- dioxide gave a dichlorophenothiazine. 3, 7-Dichloro-lO-methylphenothiazine-5-oxide ...