Tetrahedron

2-Cyanopyridazin-3 (2H)-ones: effective and chemoselective electrophilic cyanating agents

JJ Kim, DH Kweon, SD Cho, HK Kim, EY Jung, SG Lee…

Index: Kim, Jeum-Jong; Kweon, Deok-Heon; Cho, Su-Dong; Kim, Ho-Kyun; Jung, Eun-Young; Lee, Sang-Gyeong; Falck; Yoon, Yong-Jin Tetrahedron, 2005 , vol. 61, # 24 p. 5889 - 5894

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Citation Number: 31

Abstract

The introduction of a cyano group via carbon–carbon, carbon–nitrogen and carbon–sulfur forming reactions is a fundamental process in organic synthesis. Compounds containing the N-, S-, or C-cyano functional group are also found among many pharmaceuticals and their intermediates. 1 and 2 There are a limited number of reagents that can serve as a cyano cation (CN + ) equivalent or synthon, inter alia, tosyl cyanide, 3 and 4 ...

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