e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Metallo-esterification of alkynes: reaction of alkynes with Cp2ZrEt2 and chloroformate
T Takahashi, C Xi, Y Ura…
Index: Takahashi, Tamotsu; Xi, Chanjuan; Ura, Yasuyuki; Nakajima, Kiyohiko Journal of the American Chemical Society, 2000 , vol. 122, # 13 p. 3228 - 3229
Carbometalation of alkynes is a very attractive reaction for the preparation of stereodefined substituted olefins. 1 Among olefins, R, β-unsaturated ester is one of the most useful compounds in organic synthesis. Metallo-esterification of alkynes is a simple and direct preparative method of such stereodefined substituted metallo-propenoates 1 (eq 1), which can be converted into variously functionalized R, β-unsaturated esters. However, there is ...