Achieving control over the branched/linear selectivity in palladium-catalyzed allylic amination

I Dubovyk, IDG Watson, AK Yudin

Index: Dubovyk, Igor; Watson, Iain D. G.; Yudin, Andrei K. Journal of Organic Chemistry, 2013 , vol. 78, # 4 p. 1559 - 1575

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Citation Number: 18

Abstract

Palladium-catalyzed reaction of unsymmetrical allylic electrophiles with amines gives rise to regioisomeric allylic amines. We have found that linear products result from the thermodynamically controlled isomerization of the initially formed branched products. The ...