Tetrahedron

Substituent effects on the reaction mode between 2-hydroxybenzyl alcohol derivatives and MEM chloride: synthesis and mechanistic aspects of seven-and ten- …

E Saniger, M Díaz-Gavilán, B Delgado, D Choquesillo…

Index: Saniger, Estrella; Diaz-Gavilan, Monica; Delgado, Beatriz; Choquesillo, Duane; Gonzalez-Perez, Josefa M.; Aiello, Stefania; Gallo, Miguel A.; Espinosa, Antonio; Campos, Joaquin M. Tetrahedron, 2004 , vol. 60, # 50 p. 11453 - 11464

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Citation Number: 7

Abstract

The synthesis of (RS)-2-or (RS)-3-methoxy-2, 3-dihydro-5H-1, 4-benzodioxepins and (RS)-5- or (RS)-3-methoxy-2, 3, 5, 6-tetrahydro-8H-benzo-[1, 4, 7]-trioxecins has been developed. The mechanism of such a reaction via the boron trifluoride etherate-promoted transformation of 2-(methoxyethoxymethoxy) benzyloxyacetaldehyde dimethyl acetals or 2-( methoxyethoxymethoxymethyl) phenyloxyacetaldehyde dimethyl acetals has been ...