Toward Tissue-Selective Pancreatic B-Cells KATP Channel Openers Belonging to 3-Alkylamino-7-halo-4 H-1, 2, 4-benzothiadiazine 1, 1-Dioxides

P De Tullio, B Becker, S Boverie…

Index: Wollweber; Horstmann; Stoepel; Garthoff; Puls; Krause; Thomas Arzneimittel-Forschung, 1981 , vol. 31, # 2 p. 279 - 288

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Citation Number: 49

Abstract

... Volume: Page ... and several analogues described as potassium channel openers: BPDZ 44, BPDZ 83, BPDZ 73 and its quinazolinone isostere (5) in two possible tautomeric ... a (i) ClSO 2 NCO, CH 3 NO 2 , AlCl 3 ; (ii) P 2 S 5 , pyridine, Δ; (iii) NaHCO 3 , CH 3 I, CH ...