Conformational equilibrium isotope effects (in J mol− 1) have been measured for deuteriation of one methyl or methylene group in the trans stereoisomers of 1, 3- dimethylcyclohexane (− 46±10), 2, 6-(− 80±28) and 3, 5-dimethylcyclohexanone (− 40±15), and 3-methyl-(48±3) and 3-hydroxymethyl 1-trifluoromethylcyclohexane (45—49±3 in toluene, acetone or methanol). The observed effects are independent of solvent for the ...
