Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode

E Sawatzky, S Wehle, B Kling, J Wendrich…

Index: Zhao, Dan; Shen, Qi; Zhou, Yu-Ren; Li, Jian-Xin Organic and Biomolecular Chemistry, 2013 , vol. 11, # 35 p. 5908 - 5912

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Citation Number: 5

Abstract

... Journal of Medicinal Chemistry. Advanced Search. ... DOI: 10.1021/acs.jmedchem.5b01674. Publication Date (Web): February 17, 2016. Copyright © 2016 American Chemical Society. ... into toxic neurofibrillary tangles,(8-10) (iii) oxidative stress with subsequent cell death,(11, 12) and ...