Tandem additions of cuprates to benzynes. A regioselective synthesis of 3-alkyl or aryl-2-substituted benzoic acids

AI Meyers, PD Pansegrau

Index: Meyers, A. I.; Pansegrau, Paul D. Journal of the Chemical Society, Chemical Communications, 1985 , # 11 p. 690 - 691

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Citation Number: 27

Abstract

Tandem Additions of Cuprates to Benzynes. A Regioselective Synthesis of 3-Alkyl or Aryl-2-substituted Benzoic Acids ... A. 1. Meyers" and Paul 0. Pansegrau Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA ... Organocuprates add to the benzyne (2), generated in situ, to give regiospecific aromatic substitution products. ... In our continuing studies on regiocontrolled aromatic substi- tution,' mediated by the versatile oxazoline (dihydro-oxazole) group, we ...