Tetrahedron letters

An efficient procedure for the synthesis of 3-aryl-4-methoxy-2 (5H)-furanones by using the microwave-promoted Suzuki–Miyaura coupling reactions

YS Song, YJ Lee, BT Kim, JN Heo

Index: Song, Young Seob; Lee, Yun-Jeong; Kim, Bum Tae; Heo, Jung-Nyoung Tetrahedron Letters, 2006 , vol. 47, # 42 p. 7427 - 7430

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Citation Number: 23

Abstract

The Suzuki–Miyaura coupling reactions of 3-bromo-2 (5H)-furanones with a variety of arylboronic acids, promoted by microwave heating, efficiently generate 3-aryl-2 (5H)- furanones. This remarkably rapid process serves as the foundation for a simple method to rapidly construct 3-aryl-2 (5H)-furanone libraries.