Developments in Pd Catalysis: Synthesis of 1H??1, 2, 3??Triazoles from Sodium Azide and Alkenyl Bromides

J Barluenga, C Valdés, G Beltrán…

Index: Barluenga, Jose; Valdes, Carlos; Beltran, Gustavo; Escribano, Maria; Aznar, Fernando Angewandte Chemie - International Edition, 2006 , vol. 45, # 41 p. 6893 - 6896

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Citation Number: 83

Abstract

1, 2, 3-Triazoles are an important class of heterocycles which display an ample spectrum of biological activities and are widely employed as pharmaceuticals and agrochemicals. Moreover, compounds containing 1, 2, 3-triazoles have found industrial applications as dyes, corrosion inhibitors, and photostabilizers.[1] The conventional route to triazoles is the Huisgen dipolar cycloaddition of alkynes with organic azides. The development of the ...