Tetrahedron

Thiophene and its homologues as starting compounds for the preparation of aliphatic amino acids

YL Gol'dfarb, BP Fabrichnyǐ, IF Shalavina

Index: Gol'dfarb,Ya.L. et al. Tetrahedron, 1962 , vol. 18, p. 21 - 36

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Citation Number: 20

Abstract

A method for the preparation of aliphatic amino acids from thiophene and its homologues has been developed. The synthetic route to a variety of aliphatic amino acids involves the synthesis of the corresponding thiophene derivatives and subsequent Raney nickel reductive desulphurization. Long chain amino acids, both straight and branched, with a variable number of carbon atoms between the amino and the carboxylic groups have ...