Microbial O-Demethylation, Hydroxylation, Sulfation, and Ribosylation of a Xanthone Derivative from Halenia e lliptica

…, LP Zhang, KD Cheng, P Zhu, Q Wang…

Index: Yuan, Wei; Zhang, Li-Ping; Cheng, Ke-Di; Zhu, Ping; Wang, Quan; He, Hui-Xia; Zhu, Hui-Xin Journal of Natural Products, 2006 , vol. 69, # 5 p. 811 - 814

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Citation Number: 11

Abstract

1-Hydroxy-2, 3, 5-trimethoxyxanthone (1), one of the major xanthone derivatives isolated from Halenia elliptica, was biotransformed by two fungi, Trichothecium roseum and Paecilomyces marquandii. Transformation of 1 by T. roseum gave 1, 5-dihydroxy-2, 3- dimethoxyxanthone (2), 5-O-sulfate-1-hydroxy-2, 3-dimethoxyxanthone (3), 5-O-sulfate-1- hydroxy-2, 3, 7-trimethoxyxanthone (4), 5-O-β-ribofuranosyl-1-hydroxy-2, 3- ...