Double Diastereoselection in Intramolecular Photocycloadditions: A Radical Rearrangement Approach to the Total Synthesis of the Spirovetivane Phytoalexin (±)- …

MT Crimmins, Z Wang, LA McKerlie

Index: Hammoud,A.; Descoins,C. Bulletin de la Societe Chimique de France, 1978 , vol. , p. 299 - 303

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Citation Number: 43

Abstract

... Volume: Page ... Addition of the lithium enolate of ethyl acetate to acrolein at −78 °C produced the hydroxy ester 25 in 99% yield ... LDA in THF followed by addition of propargyl bromide provided the desired anti aldol product 26 in 87% yield and >95% de (Scheme 5 ...