Synthetic communications

Solvent??Free Rapid Deprotection of Ketone and Aldehyde Oximes using Periodic Acid

Z Li, RB Ding, YL Xing, SY Shi

Index: Li, Zheng; Ding, Run-Bo; Xing, Yu-Lin; Shi, Sheng-Yi Synthetic Communications, 2005 , vol. 35, # 19 p. 2515 - 2520

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Citation Number: 7

Abstract

Abstract Ketone and aldehyde oximes can be readily converted to the corresponding carbonyl compounds in high yields under solvent??free conditions when treated with periodic acid. Oximes bearing aliphatic C˭ C bonds can be selectively deoximated. The advantages of this protocol include a rapid reaction rate and a simple workup procedure. No volatile organic solvents are required in the reaction processes.