Tetrahedron

1, 2-oxazine chemistry—I: Synthetic approaches to tetrahydro-1, 2-oxazines

FG Riddell, DAR Williams

Index: Riddell,F.G.; Williams,D.A.R. Tetrahedron, 1974 , vol. 30, p. 1083 - 1086

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Citation Number: 9

Abstract

The synthesis of a series of N-carbethoxytetrahydro-1, 2-oxazines, by the reaction of 1, 4- dibromobutane derivatives with N-hydroxyurethane under basic conditions, and their reduction to N-Me derivatives is described. Stereochemical and mechanistic points of interest in these reactions are discussed.