Abstract The combination of copper (I)-Taniaphos (5 mol%) is an efficient Lewis acid catalyst for the promotion of the asymmetric 1, 3-dipolar cycloaddition of azomethine ylides to aryl vinyl sulfones, providing 3-sulfonylpyrrolidines in good yields and with nearly complete exo- selectivity and good enantiocontrol (typically 65-85% ee). The transformation of the cycloadducts into cis-2, 5-disubstituted pyrrolidines of high enantiopurity (> 99% ee) has ...
![[2]naphthyl-vinyl sulfide Structure](https://image.chemsrc.com/caspic/084/100953-47-7.png)
