e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Synlett
Transition metals in organic synthesis, part 91: palladium-catalyzed approach to 2, 6-dioxygenated carbazole alkaloids-first total synthesis of the phytoalexin …
Our interest in the natural products described above was induced by the carbalexins, described as the first carbazole-containing phytoalexins, [¹5] as well as the pharmacological potential of these compounds. In 2005, Franzblau et al. isolated lansine (5) from Micromelum hirsutum and found that it inhibits the growth of Mycobacterium tuberculosis (strain H 37 Rv). [¹8] In a cooperation with the Franzblau group, we could identify several carbazoles with promising anti-TB ...