The development of direct carbon-carbon bond formation that uses safe, environmentally benign, and low-cost starting materials remains a critical challenge for modern synthetic organic chemists. Recently, some efficient metal-catalyzed decarboxylative systems have been explored for CC bond couplings by using simple carboxylic acids as the active coupling partners. [¹] These interesting studies show that acids can replace both halides and organometallic reagents. ...
[Fujiwara, Yuta; Domingo, Victoriano; Seiple, Ian B.; Gianatassio, Ryan; Del Bel, Matthew; Baran, Phil S. Journal of the American Chemical Society, 2011 , vol. 133, # 10 p. 3292 - 3295]