Formation of arylacetic acids, arylacetamides, and aryldihydropyrroles from aromatic aldehydes

L Breen, FW Eastwood, T Ockman, ID Rae…

Index: Breen,L. et al. Australian Journal of Chemistry, 1973 , vol. 26, p. 2221 - 2227

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Citation Number: 10

Abstract

Abstract Furfuraldehyde, 4-hydroxybenzaldehyde, and 4-hydroxy-3-methoxybenzalde-hyde were converted into 2-furylacetic, 4-hydroxyphenylacetic and 4-hydroxy-3-meth- oxyphenylacetic acids respectively on reaction with glyoxal bisulphite and cyanide in alkaline solution. Under the same reaction conditions, 2-hydroxybenzaldehyde yielded 2- hydroxyphenylacetic acid and 3-(2?-hydroxypheny1)-2H-chromen-2-one. When ammonia ...