Tetrahedron

One-pot synthesis of sulfonyl (E)-stilbenes by nitrobenzene-mediated dimerizative desulfonation of benzylic sulfones

MY Chang, YC Chen, SY Lin, CK Chan

Index: Chang, Meng-Yang; Chen, Yi-Chia; Lin, Shin-Ying; Chan, Chieh-Kai Tetrahedron, 2014 , vol. 70, # 9 p. 1740 - 1747

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Citation Number: 3

Abstract

Abstract A facile one-pot synthetic route for preparing sulfonyl (E)-stilbenes 4 is developed. The efficient route is realized by a nitrobenzene (PhNO 2)-mediated dimerizative desulfonation of benzylic sulfones 3 in the presence of sodium hydride (NaH) in good yields. Some synthetic investigations of sulfonyl stilbenes 4 are also examined.