The synthesis of imidazo (b) quinoxalines was undertaken in the hope that these compounds would act as antagonists to certain structurally related essential metabolites. The imidazo (b) quinoxaline ring system was prepared by the interaction of 2, 3- diaminoquinoxalines with aldehydes, acyl halides, acid anhydrides, formic acid, orthoesters and urea. In contrast to most other fused ring imidazoles, the imidazole moiety in imidazo ( ...