Medicinal Chemistry Research

Synthesis, physicochemical properties, antimicrobial and antioxidant studies of pyrazoline derivatives bearing a pyridyl moiety

IH Lone, KZ Khan, BI Fozdar

Index: Lone, Imtiyaz Hussain; Khan, Khaliquz Zaman; Fozdar, Bharat Inder Medicinal Chemistry Research, 2014 , vol. 23, # 1 p. 363 - 369

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Citation Number: 3

Abstract

Abstract A series of new pyrazoline compounds bearing a pyridyl moiety (4a–i) were synthesized by condensing appropriate chalcones with hydrazine hydrate and tested for antimicrobial and antioxidant activities. According to in vitro antimicrobial activity against Bacillus subtilis, Staphylococcus epidermidis, Proteus vulgaris, Pseudomonas aeruginosa, Aspergillus niger and Penicillium chrysogenum and antioxidant activity by DPPH method, ...