e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Adducts of nitrous oxide and N-heterocyclic carbenes: syntheses, structures, and reactivity
AG Tskhovrebov, B Vuichoud, E Solari…
Index: Tskhovrebov, Alexander G.; Vuichoud, Basile; Solari, Euro; Scopelliti, Rosario; Severin, Kay Journal of the American Chemical Society, 2013 , vol. 135, # 25 p. 9486 - 9492
N-Heterocyclic carbenes (NHCs) react at ambient conditions with nitrous oxide to give covalent adducts. In the crystal, all compounds show a bent N2O group connected via the N- atom to the former carbene carbon atom. Most adducts are stable at room temperature, but heating induces decomposition into the corresponding ureas. Kinetic experiments show that the thermal stability of the NHC–N2O adducts depends on steric as well as electronic ...