Synthesis of haptens and protein conjugates for the development of immunoassays for the insect growth regulator fenoxycarb

…, A Székács, HM Le, BD Hammock

Index: Szurdoki; Szekacs; Le; Hammock Journal of Agricultural and Food Chemistry, 2002 , vol. 50, # 1 p. 29 - 40

Full Text: HTML

Citation Number: 41

Abstract

Sensitive and selective enzyme-linked immunosorbent assays (ELISAs) in the immobilized antigen format were developed for fenoxycarb (1), an insect growth regulator (IGR). The parent molecule [ethyl 2-(4-phenoxyphenoxy) ethylcarbamate] was derivatized at several positions to obtain haptens (2-5) that were used to produce protein conjugates and rabbit polyclonal antisera. Amino derivatives of fenoxycarb at the terminal and internal rings (2 ...