Tetrahedron

Dipyrrolidinomethylaminophosphoric acid triamide (DPMPA) as an activator for the samarium diiodide-mediated reduction of alkyl and aryl halides

CE McDonald, JR Ramsey, DG Sampsell, LA Anderson…

Index: McDonald, Chriss E.; Ramsey, Jeremy R.; Sampsell, David G.; Anderson, Laura A.; Krebs, Jordan E.; Smith, Samantha N. Tetrahedron, 2013 , vol. 69, # 14 p. 2947 - 2953

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Citation Number: 8

Abstract

The use of the conjugate base of dipyrrolidinomethylaminophosphoric triamide (DPMPA−) as an activator of samarium diiodide is reported. This phosphoramidate has been shown to be a very potent ligand, allowing for the efficient, low-temperature reduction of alkyl and aryl chlorides. Reductive cyclizations of haloalkenylnaphthalenes are also reported.