Abstract Nucleophilic substitution on vinyl halides usually occurs when these compounds possess an electron withdrawing group at the D position as well as a good leaving group at the Q position Thus D-chlorovinyl ketones are suitable starting materials for the synthesis of D-azidovinyl ketones' Nesmeyanov and Rybuiskaya2 found that this substitution proceeds with the retention of configuration regarding the C= C bond Consequently, trans-β- ...