Tetrahedron letters

Combinatorial discovery of novel fluorescent dyes based on Dapoxyl™

Q Zhu, HS Yoon, PB Parikh, YT Chang, SQ Yao

Index: Zhu, Qing; Yoon, Hai-Shin; Parikh, Puja B.; Chang, Young-Tae; Yao, Shao Q. Tetrahedron Letters, 2002 , vol. 43, # 29 p. 5083 - 5086

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Citation Number: 25

Abstract

We have developed a combinatorial method for the fast and effective synthesis of a library based on a known fluorescent dye, Dapoxyl™ using parallel solution-phase chemistry. By screening the 140 new compounds using fluorescence-based assays, we identified three new fluorescent dyes with novel properties.